Iridocorneal Endothelial Syndrome (ICE Syndrome)
Iridocorneal Endothelial Syndrome (ICE Syndrome) is a unique ophthalmic disorder that involves an irregular corneal endothelium that can lead to varying degrees of corneal edema, iris atrophy, and secondary angle-closure glaucoma.
ICE syndrome is a group of disorders with three clinical variants:
1. Chandler Syndrome
2. Essential / Progressive Iris Atrophy
3. Iris Nevus / Cogan-Reese Syndrome
Clinical distinction between each subtype can be made based on unique characteristics. However, each can result in substantial visual impairment from glaucomatous optic neuropathy and / or corneal edema, making management a challenge.
ICE syndrome is a group of disorders with three clinical variants:
1. Chandler Syndrome
2. Essential / Progressive Iris Atrophy
3. Iris Nevus / Cogan-Reese Syndrome
Clinical distinction between each subtype can be made based on unique characteristics. However, each can result in substantial visual impairment from glaucomatous optic neuropathy and / or corneal edema, making management a challenge.